Why hypoestrogenism in young women is so important?
نویسندگان
چکیده
Hypoestrogenism is referred to lower than normal serum levels of estrogen. Hypoestrogenism can be regarded as typical and physiological in postmenopausal women. However, hypoestrogenism which oocurs in young women is related to pathological background. There are two groups of disorders in young women related to hypoestrogenism: hypogonadotropic hypogonadism and hypergonadotropic hypogonadism. Hypogonadotropic hypogonadism includes hypothalamic amenorrhea, hyperprolactinemia. Hypergonadotropic hypogonadism includes gonadal dysgenesis and premature ovarian failure. Hypoestrogenism has short-term but also more long-term negative consequences for young womens’ health. It concerns skeletal system, cardiovascular system and mental problems. Young women with hypoestrogenism suffer from impairment of peak bone mass achievement, decrease of bone mass density (BMD), increase risk of bone fracture. Regarding cardiovascular system these patients are characterized by endothelial dysfunction, abnormal lipid profile. Mental disorders include depressive mood, anxiety and sexual dysfunction. Proper treatment can have positive effect on reproductive function, bone status, cardiovascular and mental health in young women.
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